Based on the Coast Guard Historian’s timeline, https://www.history.uscg.mil/research/chronology/
With inspiration from Mike Kelso

1853  The English ship Western World grounded off Spring Lake, New Jersey, during a gale with about 600 persons on board. Everyone was rescued using equipment at the nearby station.

SS Alcoa Corsair

1960  Early in the morning on October 22, 1960, SS Alcoa Corsair and SS Lorenzo Marcello collided near the mouth of the Mississippi River.  Although the Lorenzo Marcello suffered no casualties and proceeded to New Orleans, Alcoa Corsair had eight fatalities, nine injured, and one missing, besides being forced to beach because of severe damages.  A Coast Guard helicopter removed four of the critically injured crewmen while Coast Guard boats and other craft ferried the remaining ones ashore to waiting ambulances.

Northwest Airlines DC-7

1962  Shortly after a Northwest Airlines DC-7 with 102 occupants ditched in the waters of Sitka Sound, Alaska, a Coast Guard amphibian sighted five life rafts.  All on board survived, although three suffered minor injuries.  A Federal Aviation Administration supply boat picked up the survivors, later transferring them to CGC Sorrel, which took them to Sitka, Alaska.

USCGC Charles Sexton (WPC-1108). US Coast Guard photo.

2014  The crew of CGC Charles David Jr. repatriated 43 Cuban migrants to Bahia de Cabañas, Cuba. These repatriations were a result of three separate interdictions of people attempting to illegally migrate to the United States. On October 18, 2014, the crew of CGC Charles Sexton interdicted 22 Cuban migrants from two separate interdictions in the Florida Straits. The next day, October 19, Sexton interdicted another 21 Cuban migrants. All of the migrants were safely removed from their makeshift vessels and were transferred to the Charles David Jr. for repatriation.