Naval News reports the seizure of an unmanned low profile, semi-submersible that was used to transport illegal drugs.
Not only would semi-autonomous operation eliminate the cost of hiring a crew and the space requirements for accommodations to support the crew, it would also eliminate the possibility of a captured crew becoming a source of intelligence for law enforcement.
It also means that upon boarding there is no one to tell to stop the engines, meaning boardings may be more dangerous than ever.
I would not be surprised to see a remote scuttling option incorporated into future designs.

Remote detonation would also work – get rid of the evidence and the boarding party. But there might be some evidence in the satellite link –