(The Navy does love acronyms)
This is the name of a Commercial Off The Shelf (COTS) based system that uses a fiber optic local area network to assemble and evaluate information from sensors, and recommend or even initiate actions to defend ships from cruise missile attack. Apparently the Navy intends to extend it in some form to all non-Aegis ship down to the Littoral Combat Ship.
Systems that have been integrated into the system include the AN/SPQ-9B radar, the AN/SLQ-32 Electronic Attack System, the NULKA missile decoy system, Mk 15 Phalanx Close-In Weapon System. If they sound familiar it may be because they are all on the National Security Cutter and may be on the Offshore Patrol cutter as well.
Defense Industry Daily reviews the program here.